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Edward Sako, MD

UT Health San Antonio
Schedule an appointment: 210-450-0999
Cardiothoracic Surgery
Board Affiliation/Certification
American Board of Surgery
American Board of Thoracic Surgery
University of Minnesota Medical School-Minneapolis, 1982
University of Minnesota School of Medicine, 1990
University of Michigan Medical School, 1992

Medical Arts & Research Center

8300 Floyd Curl Drive
San Antonio,TX 78229

University Hospital

4502 Medical Drive
San Antonio,TX 78229
Insurance Accepted
6 Degrees - Transplant
90 Degree Benefits - Commercial
Aetna - PPO/EPO/HMO/MC Advantage
Aetna - Smart Care EPO
Aetna - Transplant
Aetna Better Health - Medicaid-CHIP
Aetna Better Health - Medicaid-STAR
AIG - Transplant
Amerigroup - Medicaid-CHIP
Amerigroup - Medicaid-CHIP Perinate
Amerigroup - Medicaid-STAR
Amerigroup - Medicaid-STAR Kids
Amerigroup - Medicaid-STAR PLUS
Amerigroup - Medicare Advantage
Amerigroup - Medicare-Medicaid Duals
Ancira Enterprises - Direct Employer
Blue Cross Blue Shield of Texas - Exchange (BlueAdvantage)
Blue Cross Blue Shield of Texas - HMO/PPO
Blue Cross Blue Shield of Texas - HPN/EPO (Narrow Network)
Blue Cross Blue Shield of Texas - Medicaid-STAR
Blue Cross Blue Shield of Texas - Medicare Advantage HMO
Blue Cross Blue Shield of Texas - Medicare Advantage PPO
Blue Cross Blue Shield of Texas - Narrow HMO (Blue Essentials)
Blue Cross Blue Shield of Texas - Narrow HMO (Blue Premier)
Blue Cross Blue Shield of Texas - Traditional
Blue Cross Blue Shield of Texas - Transplant Programs
Care Improvement Plus - Medicare Advantage-SNP
Cenpatico - Medicaid-CHIP
Cenpatico - Medicaid-STAR
Cenpatico - Medicaid-STAR Health (Foster Care)
Cenpatico - Medicare Advantage
Community First Health Plans - HMO/Exchange (EPO)
Community First Health Plans - Medicaid-CHIP
Community First Health Plans - Medicaid-CHIP Perinate
Community First Health Plans - Medicaid-STAR
Community First Health Plans - Medicaid-STAR Kids
Community First Health Plans - Medicare Advantage HMO
Coventry - HMO/PPO
Coventry - Work Comp / Auto
Decent Health Plan - Commercial EPO
Entrust - TPA
FirstCare (Part of Scott & White Health Plans) - Medicaid-STAR
Healthsmart - PPO
Humana - Commercial Behavioral Health
Humana - Exchange (HMOx)
Humana - HMO/PPO/Behavioral Health
Humana - Medicare Advantage Behavioral Health
Humana - Medicare Advantage HMO (Gold)
Humana - Medicare Advantage PPO
Humana - National Transplant Network
Humana Military - TRICARE
Imperial Health Plan - Medicare Advantage
Independent Medical Systems (IMS) - PPO
Interlink - Transplant
LifeTrac - Transplant
Magellan - Commercial and Medicaid Behavioral Health
Molina - Commercial Exchange
Molina - Medicaid-CHIP
Molina - Medicaid-CHIP Perinate
Molina - Medicaid-STAR
Molina - Medicare Advantage
Molina - Medicare-Medicaid Duals
OptumHealth - Transplant
Point Comfort Underwriters (PCU) - Refugee Medical Assistance
Point Comfort Underwriters (PCU) - Unaccompanied Children
Preferred Provider Health Plan (PPHP) - Medicare Advantage I-SNP
Prime Health Services - Medicare Advantage
Prime Health Services- PPO
ProCare Advantage - Medicare Advantage I-SNP
Scott & White Health Plan - HMO/PPO/Medicare Advantage
Superior HealthPlan - Medicaid-CHIP
Superior HealthPlan - Medicaid-CHIP Perinate
Superior HealthPlan - Medicaid-STAR
Superior HealthPlan - Medicaid-STAR Health (Foster Care)
Superior HealthPlan - Medicaid-STAR Kids
Superior HealthPlan - Medicaid-STAR PLUS
Superior HealthPlan - Medicare Advantage (Allwell)
Superior HealthPlan - Medicare-Medicaid Duals (Allwell)
Texas Independence Health Plan - Medicare Advantage I-SNP
Three Rivers Provider Network - PPO
TriWest (via BCBSTX) - VA CCN Program
UnitedHealthcare - Medicaid-STAR
UnitedHealthcare - Medicaid-STAR Kids
UnitedHealthcare - Medicaid-STAR PLUS
UnitedHealthcare - Medicare Advantage
UnitedHealthcare - PPO
University of Incarnate Word - Direct Employer
WellCare - Medicare Advantage
WellMed - Medicare Advantage
Please contact your health insurance company to confirm provider participation. For billing and insurance questions, please call our Billing Department at 210-358-3260.
I strive to provide the best possible patient care while simultaneously fulfilling the academic mission of education and the search for new knowledge.
When I’m not practicing medicine, I enjoy bicycling, traveling, spending time outdoors and photography. I also enjoy watching sports with family, including football, bicycle racing and Formula 1 races.
I completed medical school and my general surgery residency at the University of Minnesota. I also completed a thoracic surgery residency at the University of Michigan. I spent 30 years as faculty member in Cardiothoracic Surgery at UT Health San Antonio and at the South Texas Veterans Health Care System.

Journal Articles

  1. Katona MA, Walker JL, Das NA, Miller SR, Sako EY. .Using a quality improvement initiative to reduce acute kidney injury during on-pump coronary artery bypass grafting. Perfusion 2020 Jun .
  2. Genuth SM, Vlachos H, Brooks MM, Bantle JP, Chaitman BR, Green J, Kelsey SF, King SB 3rd, McBane R, Sako EY, Schneider DJ, Steffes M, Frye RL..BARI 2D Study Group. BARI 2D: A Reanalysis Focusing on Cardiovascular Events. Mayo Clin Proc 2019 Nov;94(11):2249-2262. .
  3. Oglesby M, Escobedo D, Escobar GP, Fatemifar F, Sako EY, Bailey SR, Han HC, Feldman MD. .Trabecular cutting: a novel surgical therapy to increase diastolic compliance. J Appl Physiol 2019 Aug;127(2):457-463..
  4. Pruthi DK, Wang H, Satsangi A, Cajipe M, Iffrig K, Haidar GM, Hicks T, Sako EY, Liss MA, Chowdhury WH, Rodriguez R, Kaushik D. .Contemporary surgical outcomes of venous tumour thrombectomy managed with intraoperative Doppler ultrasound for kidney cancer Can Urol Assoc J 2018 May .
  5. Singh A, Schaff HV, Mori Brooks M, Hlatky MA, Wisniewski SR, Frye RL, Sako EY; BARI 2D Study Group..On-pump versus off-pump coronary artery bypass graft surgery among patients with type 2 diabetes in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial Eur J Cardiothor Surg 2016 Feb;49(2):406-416. .
  6. Adams AJ, Wasson EA, Admire JR, Gomez PP, Babayeuski RA, Sako EY, Willis RE. .A comparison of teaching modalities and fidelity of simulation levels in teaching resuscitation scenarios Journal of Surg Ed 2015 Sep;72(5):778-785. .
  7. Adkins A, Aleman J, Boies L, Sako E, Bhattacharya S, Sako EY. .Force Required to Cinch the Tricuspid Annulus: An Ex-Vivo Study. J Heart Valve Dis 2015 Sep;24(5):644-652. .
  8. Copeland LA, Zeber JE, Sako EY, Mortensen EM, Pugh MJ, Wang CP, Restrepo MI, Flynn J, MacCarthy AA, Lawrence VA..Serious mental illnesses associated with receipt of surgery in retrospective analysis of patients in the Veterans Health Administration. BMC Surg 2015 Jun;15(74):doi:10 .
  9. Sako EY, Brooks MM, Hardison RM, Schaff H, Frye RL. .Coronary artery bypass in patients with type 2 diabetes: experience from the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial J Thorac Cardiovasc Surg 2014 Oct;148(4):1268-1272..
  10. Bayer J, Das NA, Basiden CE, Rani M, Schwacha MG, Sako EY, Williams RO, Peters JI, Johnson SB. .Effect of inhaled tacrolimus on ischemia reperfusion injury in a rat lung transplant model. The Journal of Thoracic and Cardiovascular Surgery 2013 Sep;146(5):1213-1219. .
  11. Brooks MM, Chaitman BR, Nesto RW, Hardison RM, Feit F, Gersh BJ, Krone RJ, Sako EY, Rogers WJ, Garber AJ, King SB, Davidson CJ, Ikeno F, Frye RL. .Clinical and Angiographic Risk Stratification and Differential Impact on Treatment Outcomes in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial. Circulation 2012 Oct;126(17):2115-2124. .
  12. Argenziano M, Skipper E, Heimansohn D, Letsou GV, Woo YJ, Kron I, Alexander J, Cleveland J, Kong B, Davidson M, Vassiliades T, Krieger K, Sako E, Tibi P, Galloway A, Foster E, Feldman T, Glower D, Sako EY. .Surgical revision after percutaneous mitral repair with the MitraClip device. Ann Thorac Surg 2010 Jan;89(1):72-80. .
  13. BARI 2D Study Group, Frye, RL, August, P, Brooks, M, Hardison, R, Kelsey, S, MacGregor, J, Orchard, T, Chaitman, B, Genuth, S, Goldberg, S, Hlatky, M, Jones, TLZ, Molich, M, Nesto, R, Sako EY, Sobel, B..A randomized trial of therapies for type 2 diabetes and coronary artery disease. New England Journal of Medicine 2009 Jun;360(24):2503-2515. .
  14. Angel LF, Levine DJ, Restrepo MI, Johnson S, Sako E, Carpenter A, Calhoon J, Cornell JE, Adams SG, Chisholm GB, Nespral J, Roberson A, Levine SM, Calhoon JH. .Impact of a lung transplantation donor-management protocol on lung donation and recipient outcomes. Am J Respir Crit Care Med 2006 Sep;174(6):710-716. .
  15. Johnson SB, Allred AM, Cline AM, Angel LF, Sako EY, Baisden CE, Calhoon JH. .Cardiac procedures in lung transplant recipients do not increase mortality in selected patients. Ann Thorac Surg 2006 Aug;82(2):460-464. .
  16. Sako EY, Petrusa ER, Paukert JL. .Factors influencing outcome of the American Board of Surgery Certifying examination: an observational study. J Surg Res 2002 Jun;105(2):75-80. .
  17. Homma A, Anzueto A, Peters JI, Susanto I, Sako E, Zabalgoitia M, Bryan CL, Levine SM. .Pulmonary artery systolic pressures estimated by echocardiogram vs cardiac catheterization in patients awaiting lung transplantation J Heart Lung Transpl 2001 Aug;20(8):833-839. .
  18. Angel LF, Cai TH, Sako EY, Levine SM..Posttransplant lymphoproliferative disorders in lung transplant recipients: clinical experience at a single center. Ann Transplant 2000;5(3):26-30..
  19. Patterson JE, Peters J, Calhoon, JH, Levine S, Anzueto A, Al-Abdely H, Sanchez R, Patterson TF, Rech M, Jorgensen JH, Rinaldi MG, Sako E, Johnson S, Speeg V, Halff GA, Trinkle JK..Investigation and control of aspergillosis and other filamentous fungal infections in solid organ transplant recipients Transpl Infect Dis 2000 Mar;2(1):22-28. .
  20. Cai TH, Moody JM, Sako EY. .Mitral valve aneurysm due to severe aortic valve regurgitation. Circulation 1999 Sep;100(12):53-56. .
  21. Susanto I, Peters JI, Levine SM, Sako EY, Anzueto A, Bryan CL. .Use of balloon expandable metallic stents in the management of bronchial stenosis and bronchomalacia after lung transplantation. Chest 1998 Nov;114(5):1330-1335. .
  22. Undar A, Holland MC, Howelton RV, Benson CK, Ybarra JR, Miller OL, Rossbach MM, Runge TM, Johnson SB, Sako EY, Calhoon JH. .Testing neonate-infant membrane oxygenators with the University of Texas neonatal pulsatile cardiopulmonary bypass system in vitro. Perfusion 1998 Sep;13(5):346-352. .
  23. Rossbach MM, Johnson SB, Gomez MA, Sako EY, Miller OL, Calhoon JH. .Management of major tracheobronchial injuries: a 28-year experience. Ann Thorac Surg 1998 Jan;65(1):182-186. .
  24. Pollard TR, Schwesinger WH, Sako EY, Sirinek KR. .Abdominal operations after lung transplantation. Indications and outcome. Arch Surg 1997 Jul;132(7):714-718..
  25. Patterson TF, Peters J, Levine SM, Anzueto A, Bryan CL, Sako EY, Miller OL, Calhoon JH, Rinaldi MG. .Systemic availability of itraconazole in lung transplantation. Antimicrob Agents Chemother 1996 Sep;40(9):2217-2220..
  26. Sako EY, Miller OL, Calhoon JH..Lung donor selection, management, and preservation Seminars in Resp and Critical Care Medicine 1996 Mar;17:119-127..
  27. Calhoon JH, Bunegin L, Gelineau JF, Felger MC, Naples JJ, Miller OL, Sako EY. .Twelve-hour canine heart preservation with a simple, portable hypothermic organ perfusion device. Ann Thorac Surg 1996;62(1):91-93..
  28. Levine SM, Anzueto A, Peters JI, Cronin T, Sako EY, Jenkinson SG, Bryan CL..Medium term functional results of single-lung transplantation for endstage obstructive lung disease Am J Respir Crit Care Med 1994 Aug;150(2):398-402..
  29. Kingsley PB, Sako EY, Yang MQ, Zimmer SD, Ugurbil K, Foker JE, From AH..Ischemic contracture begins when anaerobic glycolysis stops: a 31P-NMR study of isolated rat hearts. Am J Physiol 1991 Aug;261(2 Pt):469-478. .
  30. Kingsley-Hickman PB, Sako EY, Ugurbil K, From AH, Foker JE. .31P NMR measurement of mitochondrial uncoupling in isolated rat hearts. J Biol Chem 1990 Jan;265(3):1545-1550..
  31. Mahoney JR, Sako EY, Seymour KM, Marquardt CA, Foker JE..A comparison of different carbohydrates as substrates for the isolated working heart. J Surg Res 1989 Dec;47(6):530-534..
  32. Sako EY, Kingsley-Hickman PB, From AH, Foker JE, Ugurbil K..ATP synthesis kinetics and mitochondrial function in the postischemic myocardium as studied by 31P NMR. J Biol Chem 1988 Aug;263(22):10600-10607..
  33. Sako EY, Kingsley-Hickman PB, From AH, Ugurbil K, Foker JE..Substrate effects in the post-ischemic myocardium. J Surg Res 1988 Apr;44(4):430-435..
  34. Ugurbil K, Kingsley-Hickman PB, Sako EY, Zimmer S, Mohanakrishnan P, Robitaille PM, Thoma WJ, Johnson A, Foker JE, From AH. .31P NMR studies of the kinetics and regulation of oxidative phosphorylation in the intact myocardium. Ann N Y Acad Sci 1987;508:265-286..
  35. Kingsley-Hickman PB, Sako EY, Mohanakrishnan P, Robitaille PM, From AH, Foker JE, Ugurbil K. .31P NMR studies of ATP synthesis and hydrolysis kinetics in the intact myocardium. Biochemistry 1987 Nov;26(23):7501-7510. .
  36. Sako EY, Kingsley-Hickman PB, St. Cyr JA, Andreone PG, Ugurbil K, Foker JE..Dobutamine increases efficiency of ATP utilization in the postischemic isolated heart Surg Forum 1986;37:236-238..
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