Pediatric Liver Tumors

Liver tumors can affect children and adolescents. These tumors could be benign (hemangiomas, FNH) or malignant (HCC, cholangiocarcinoma). 

There are a few conditions that have been associated with the development of certain liver tumors in the pediatric age group including the following:

  • Glycogen storage disorders → adenomas
  • Tyrosinemia and progressive familiar intrahepatic cholestasis → HCC
  • Familial adenomatous polyposis → hepatoblastoma

Hepatoblastoma is a malignant liver tumor that is unique to the pediatric population and primarily affects younger infants and children. Hepatoblastoma can involve large sections of the liver and may metastasize to other organs including the lungs. Fortunately, hepatoblastoma is very responsive to chemotherapy and a cure is feasible with appropriate multidisciplinary treatment that may include surgery, chemotherapy and occasionally liver transplantation.